Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7907.017 | 0.7823 | 0.6816 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7907.017 | 0.2110 | -0.3337 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7907.017 | 0.0582 | -0.7316 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7907.017 | 0.0143 | -0.9004 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7907.017 | 0.0049 | -0.9533 | 1.4157 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9797.017 | 1.0354 | 1.1497 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9797.017 | 0.8708 | 0.5014 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 9797.017 | 0.9335 | 0.7341 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9797.017 | 0.7762 | 0.1830 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 9797.017 | 0.6721 | -0.1223 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 9797.017 | 0.3624 | -0.7560 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 9797.017 | 0.0240 | -0.9991 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 9797.017 | 0.0250 | -0.9990 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 9797.017 | 0.0003 | -1.0000 | 0.4824 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9830.017 | 1.1106 | 1.1162 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9830.017 | 1.0385 | 1.0411 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 9830.017 | 1.0653 | 1.0693 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9830.017 | 0.8710 | 0.8567 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 9830.017 | 0.5803 | 0.4921 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 9830.017 | 0.0858 | -0.4669 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 9830.017 | 0.0114 | -0.8205 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 9830.017 | 0.0118 | -0.8170 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 9830.017 | 0.0003 | -0.9769 | 1.8576 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7918.017 | 0.9546 | 0.9710 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7918.017 | 0.9984 | 0.9990 | 3.1833 |