Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9860.017 | 1.0072 | 1.0084 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9860.017 | 0.9511 | 0.9424 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 0.011 | uM | 9860.017 | 1.0254 | 1.0294 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9860.017 | 0.9202 | 0.9054 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 0.276 | uM | 9860.017 | 0.6071 | 0.4953 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 1.38 | uM | 9860.017 | 0.1528 | -0.3309 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 6.9 | uM | 9860.017 | 0.2560 | -0.0961 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 34.5 | uM | 9860.017 | 0.2155 | -0.1823 | 1.7158 | |
| SUM229PE | TNBC | - | Epirubicin | TOP2 | TOP | 172 | uM | 9860.017 | 0.0008 | -0.9694 | 1.7158 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7923.017 | 0.7525 | 0.2706 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7923.017 | 0.7015 | 0.1360 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7923.017 | 0.8835 | 0.6414 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7923.017 | 0.7015 | 0.1360 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7923.017 | 0.5630 | -0.2002 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7923.017 | 0.1226 | -0.9298 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7923.017 | 0.0872 | -0.9592 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7923.017 | 0.0017 | -0.9999 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7923.017 | 0.0020 | -0.9999 | 0.6267 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9878.017 | 0.9929 | 0.9895 | 1.3463 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9878.017 | 1.0468 | 1.0691 | 1.3463 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9878.017 | 0.9846 | 0.9771 | 1.3463 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9878.017 | 0.9514 | 0.9274 | 1.3463 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9878.017 | 0.7225 | 0.5710 | 1.3463 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9878.017 | 0.1366 | -0.5440 | 1.3463 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9878.017 | 0.1825 | -0.4347 | 1.3463 |