Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9878.017 | 0.1276 | -0.5667 | 1.3463 | |
| SUM52PE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9878.017 | 0.0002 | -0.9967 | 1.3463 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7926.017 | 0.9457 | 0.8783 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7926.017 | 0.9304 | 0.8441 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7926.017 | 1.1227 | 1.2778 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7926.017 | 0.9184 | 0.8174 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7926.017 | 0.7462 | 0.4391 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7926.017 | 0.1668 | -0.7329 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7926.017 | 0.3421 | -0.4011 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7926.017 | 0.3423 | -0.4007 | 0.8896 | |
| UACC-812 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7926.017 | 0.8887 | 0.7516 | 0.8896 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7931.017 | 1.0332 | 1.0490 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7931.017 | 0.9421 | 0.9135 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7931.017 | 0.9970 | 0.9955 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7931.017 | 0.9087 | 0.8629 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7931.017 | 0.7080 | 0.5483 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7931.017 | 0.2740 | -0.2341 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7931.017 | 0.4392 | 0.0866 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7931.017 | 0.2743 | -0.2334 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7931.017 | 0.0045 | -0.9634 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7932.017 | 0.9951 | 0.9908 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7932.017 | 0.9497 | 0.9059 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7932.017 | 1.0164 | 1.0305 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7932.017 | 0.9948 | 0.9902 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7932.017 | 0.5483 | 0.1413 | 1.0712 |