Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9583.017 | 1.0595 | 1.1136 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9583.017 | 0.9974 | 0.9951 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9583.017 | 1.0158 | 1.0302 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9583.017 | 0.9516 | 0.9073 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9583.017 | 0.7438 | 0.5069 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9583.017 | 0.3195 | -0.3284 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9583.017 | 0.5332 | 0.0960 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9583.017 | 0.3882 | -0.1908 | 1.0456 | |
| MCF7 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9583.017 | 0.0010 | -0.9973 | 1.0456 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7876.017 | 1.2705 | 1.8582 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7876.017 | 0.7644 | 0.3397 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7876.017 | 0.7652 | 0.3419 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7876.017 | 0.9703 | 0.9120 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7876.017 | 1.1195 | 1.3668 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7876.017 | 0.4300 | -0.4319 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7876.017 | 0.1613 | -0.8684 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7876.017 | 0.1373 | -0.8965 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7876.017 | 0.0120 | -0.9973 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7877.017 | 1.0364 | 1.1055 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7877.017 | 1.0352 | 1.1020 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7877.017 | 1.0513 | 1.1491 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7877.017 | 1.0276 | 1.0798 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7877.017 | 0.9649 | 0.8999 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7877.017 | 0.7987 | 0.4477 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7877.017 | 0.6634 | 0.1087 | 0.6955 |