Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 10938.156 | 0.5805 | 0.0972 | 0.9058 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 10938.156 | 0.5607 | 0.0560 | 0.9058 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12333.156 | 0.9742 | 0.9181 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12333.156 | 0.8334 | 0.4940 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12333.156 | 0.7837 | 0.3540 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12333.156 | 0.6141 | -0.0836 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12333.156 | 0.5699 | -0.1869 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12333.156 | 0.5631 | -0.2023 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12333.156 | 0.5304 | -0.2753 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12333.156 | 0.5184 | -0.3013 | 0.6247 | |
| MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12333.156 | 0.4015 | -0.5359 | 0.6247 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12414.164 | 0.9955 | 0.9928 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12414.164 | 0.9784 | 0.9654 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12414.164 | 0.9428 | 0.9083 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12414.164 | 0.7583 | 0.6042 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12414.164 | 0.3576 | -0.1188 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12414.164 | 0.4473 | 0.0534 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12414.164 | 0.4003 | -0.0358 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12414.164 | 0.4052 | -0.0265 | 1.2548 | |
| MDA-MB-453 | TNBC | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12414.164 | 0.0952 | -0.6931 | 1.2548 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.000171 | uM | 10874.156 | 0.9903 | 0.9720 | 0.6949 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.000853 | uM | 10874.156 | 1.0447 | 1.1298 | 0.6949 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.00427 | uM | 10874.156 | 0.9460 | 0.8463 | 0.6949 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.0213 | uM | 10874.156 | 1.0014 | 1.0040 | 0.6949 | |
| MX1 | Unknown | Unknown | Everolimus | MTOR | MTOR | 0.107 | uM | 10874.156 | 0.7661 | 0.3630 | 0.6949 |