Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 10999.156 | 1.0952 | 1.4044 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 10999.156 | 1.2213 | 1.9979 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 10999.156 | 0.9450 | 0.7838 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 10999.156 | 0.9490 | 0.7987 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 10999.156 | 0.6669 | -0.1193 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 10999.156 | 0.7433 | 0.0970 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 10999.156 | 0.6189 | -0.2427 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 10999.156 | 0.6153 | -0.2517 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 10999.156 | 0.3637 | -0.7418 | 0.4940 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 12379.164 | 0.9635 | 0.8348 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 12379.164 | 0.9576 | 0.8092 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 12379.164 | 0.8729 | 0.4600 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 12379.164 | 0.8007 | 0.1954 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 12379.164 | 0.6703 | -0.2081 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 12379.164 | 0.6443 | -0.2773 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 12379.164 | 0.5911 | -0.4081 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12379.164 | 0.5899 | -0.4108 | 0.4318 | |
MDA-MB-361 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12379.164 | 0.2956 | -0.8811 | 0.4318 | |
MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 10938.156 | 1.0377 | 1.0834 | 0.9058 | |
MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 10938.156 | 0.9492 | 0.8882 | 0.9058 | |
MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 10938.156 | 1.0196 | 1.0433 | 0.9058 | |
MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 10938.156 | 0.8805 | 0.7379 | 0.9058 | |
MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 10938.156 | 0.6022 | 0.1425 | 0.9058 | |
MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 10938.156 | 0.6022 | 0.1426 | 0.9058 | |
MDA-MB-415 | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 10938.156 | 0.5977 | 0.1331 | 0.9058 |