Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9146.049 | 0.2507 | -0.4278 | 1.1054 | |
| AU565 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9146.049 | 0.0892 | -0.7753 | 1.1054 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7797.016 | 1.0096 | 1.0373 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7797.016 | 0.8936 | 0.6078 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7797.016 | 0.9198 | 0.7005 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7797.016 | 0.9915 | 0.9672 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7797.016 | 0.8661 | 0.5134 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7797.016 | 0.8464 | 0.4471 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7797.016 | 0.6998 | 0.0007 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7797.016 | 0.5036 | -0.4714 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7797.016 | 0.1207 | -0.9669 | 0.5155 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9158.049 | 0.9074 | 0.5764 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9158.049 | 1.0602 | 1.3078 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9158.049 | 0.9984 | 0.9922 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9158.049 | 0.8880 | 0.4950 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9158.049 | 0.9557 | 0.7899 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9158.049 | 1.0018 | 1.0089 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9158.049 | 0.9561 | 0.7919 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9158.049 | 0.2697 | -0.9194 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9158.049 | 0.0028 | -1.0000 | 0.4082 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9163.024 | 1.0717 | 1.2670 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9163.024 | 1.0483 | 1.1784 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9163.024 | 1.0526 | 1.1943 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9163.024 | 0.6091 | -0.1848 | 0.5524 | |
| BT-474 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9163.024 | 1.0492 | 1.1818 | 0.5524 |