Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7877.017 | 1.0547 | 1.1592 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7877.017 | 1.0419 | 1.1214 | 0.6955 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7879.017 | 0.8783 | 0.8590 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7879.017 | 1.0523 | 1.0582 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7879.017 | 1.0193 | 1.0216 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7879.017 | 0.8581 | 0.8348 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7879.017 | 0.8802 | 0.8613 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7879.017 | 0.0815 | -0.5127 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7879.017 | 0.0223 | -0.7651 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7879.017 | 0.0181 | -0.7909 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7879.017 | 0.9341 | 0.9247 | 1.7754 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7885.017 | 0.9603 | 0.8615 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7885.017 | 0.9707 | 0.8975 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7885.017 | 0.9708 | 0.8977 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7885.017 | 0.9347 | 0.7746 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7885.017 | 0.7705 | 0.2605 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7885.017 | 0.2891 | -0.7779 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7885.017 | 0.5632 | -0.2765 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7885.017 | 0.3347 | -0.7122 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7885.017 | 0.0002 | -1.0000 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7886.017 | 1.0193 | 1.0534 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7886.017 | 1.0071 | 1.0196 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7886.017 | 0.9878 | 0.9662 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7886.017 | 0.9346 | 0.8212 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7886.017 | 0.7087 | 0.2422 | 0.7230 |