Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7833.017 | 1.0336 | 1.0517 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7833.017 | 0.9794 | 0.9681 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7833.017 | 1.0560 | 1.0858 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7833.017 | 0.9776 | 0.9654 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7833.017 | 0.8037 | 0.6901 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7833.017 | 0.6210 | 0.3853 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7833.017 | 0.5826 | 0.3188 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7833.017 | 0.5776 | 0.3101 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7833.017 | 1.0479 | 1.0734 | 1.2975 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7837.017 | 1.0865 | 1.1198 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7837.017 | 1.0133 | 1.0187 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7837.017 | 1.0044 | 1.0061 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7837.017 | 0.8526 | 0.7884 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7837.017 | 0.6601 | 0.4945 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7837.017 | 0.1071 | -0.5828 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7837.017 | 0.0443 | -0.7753 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7837.017 | 0.0317 | -0.8223 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7837.017 | 0.0007 | -0.9883 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9386.017 | 1.0285 | 1.0416 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9386.017 | 0.9457 | 0.9200 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 9386.017 | 1.0603 | 1.0876 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9386.017 | 0.7947 | 0.6904 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 9386.017 | 0.6383 | 0.4400 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 9386.017 | 0.1785 | -0.4331 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 9386.017 | 0.0838 | -0.6741 | 1.3666 |