Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9047.017 | 1.0255 | 1.0605 | 0.8440 | |
| 184A1 | NM | Basal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9047.017 | 1.0945 | 1.2259 | 0.8440 | |
| 184A1 | NM | Basal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9047.017 | 0.6717 | 0.2481 | 0.8440 | |
| 184A1 | NM | Basal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9047.017 | 0.3368 | -0.4491 | 0.8440 | |
| 184A1 | NM | Basal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9047.017 | 0.0893 | -0.8858 | 0.8440 | |
| 184A1 | NM | Basal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9047.017 | 0.0331 | -0.9648 | 0.8440 | |
| 184A1 | NM | Basal | Epirubicin | TOP2 | TOP | 172 | uM | 9047.017 | 0.0002 | -0.9999 | 0.8440 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9118.017 | 1.0336 | 1.0645 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9118.017 | 0.9677 | 0.9379 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9118.017 | 1.0074 | 1.0142 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9118.017 | 0.9606 | 0.9242 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9118.017 | 0.8242 | 0.6607 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9118.017 | 0.2328 | -0.5074 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9118.017 | 0.4277 | -0.1162 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9118.017 | 0.4610 | -0.0500 | 1.0401 | |
| 600MPE | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9118.017 | 0.4000 | -0.1712 | 1.0401 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7793.035 | 0.9941 | 0.9902 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7793.035 | 0.9720 | 0.9537 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7793.035 | 1.0085 | 1.0140 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7793.035 | 0.9559 | 0.9269 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7793.035 | 0.2445 | -0.3743 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7793.035 | 0.0734 | -0.7681 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7793.035 | 0.0126 | -0.9459 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7793.035 | 0.0100 | -0.9553 | 1.2119 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7793.035 | 0.0013 | -0.9918 | 1.2119 |