Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7531.074 | 1.0989 | 1.0589 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7531.074 | 1.0079 | 1.0049 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7531.074 | 1.0381 | 1.0232 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7531.074 | 0.9499 | 0.9686 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7531.074 | 0.5764 | 0.6880 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7531.074 | 0.2748 | 0.3438 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7531.074 | 0.1051 | -0.0003 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7531.074 | 0.0382 | -0.2678 | 3.2488 | |
| SUM159PT | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7531.074 | 0.0047 | -0.6168 | 3.2488 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7532.074 | 1.0780 | 1.2042 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7532.074 | 1.0125 | 1.0325 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7532.074 | 1.0311 | 1.0808 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7532.074 | 0.9741 | 0.9333 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7532.074 | 0.8750 | 0.6825 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7532.074 | 0.8425 | 0.6021 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7532.074 | 0.7349 | 0.3426 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7532.074 | 0.5798 | -0.0121 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7532.074 | 0.4918 | -0.2017 | 0.7728 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7533.074 | 1.0097 | 1.0183 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7533.074 | 1.0608 | 1.1140 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7533.074 | 1.0234 | 1.0439 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7533.074 | 1.0474 | 1.0889 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7533.074 | 1.0567 | 1.1063 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7533.074 | 1.0009 | 1.0018 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7533.074 | 0.6115 | 0.2602 | 1.0648 |