Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7533.074 | 0.4527 | -0.0499 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7533.074 | 0.4575 | -0.0405 | 1.0648 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7534.074 | 1.1055 | 1.1905 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7534.074 | 0.9872 | 0.9767 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7534.074 | 1.0091 | 1.0166 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7534.074 | 0.9622 | 0.9314 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7534.074 | 1.0538 | 1.0974 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7534.074 | 0.9949 | 0.9908 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7534.074 | 0.6363 | 0.3274 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7534.074 | 0.5065 | 0.0791 | 1.1026 | |
| SUM225CWN | HER2amp | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7534.074 | 0.4696 | 0.0076 | 1.1026 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.000853 | uM | 7535.074 | 0.9522 | 0.9089 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.00427 | uM | 7535.074 | 0.9887 | 0.9786 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.0213 | uM | 7535.074 | 0.9635 | 0.9305 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.107 | uM | 7535.074 | 0.9201 | 0.8476 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.533 | uM | 7535.074 | 0.8283 | 0.6717 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 2.67 | uM | 7535.074 | 0.4291 | -0.1060 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 13.3 | uM | 7535.074 | 0.1695 | -0.6306 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 66.7 | uM | 7535.074 | 0.0831 | -0.8127 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 333 | uM | 7535.074 | 0.1204 | -0.7334 | 1.0507 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.000853 | uM | 7537.074 | 0.9325 | 0.9316 | 2.0080 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.00427 | uM | 7537.074 | 0.9628 | 0.9626 | 2.0080 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.0213 | uM | 7537.074 | 0.9614 | 0.9612 | 2.0080 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.107 | uM | 7537.074 | 0.8900 | 0.8872 | 2.0080 | |
| SUM229PE | TNBC | - | Etoposide | TOP2 | TOP | 0.533 | uM | 7537.074 | 0.7083 | 0.6844 | 2.0080 |