Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 11056.154 | 0.8665 | 0.9047 | 2.9341 | |
| MCF 10A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 11056.154 | 0.9834 | 0.9886 | 2.9341 | |
| MCF 10A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 11056.154 | 0.8544 | 0.8956 | 2.9341 | |
| MCF 10A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 11056.154 | 1.0759 | 1.0505 | 2.9341 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 12254.154 | 1.0417 | 1.0507 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 12254.154 | 1.0727 | 1.0880 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 12254.154 | 1.0619 | 1.0750 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 12254.154 | 1.0653 | 1.0791 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 12254.154 | 1.0471 | 1.0572 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 12254.154 | 1.0090 | 1.0110 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 12254.154 | 1.1296 | 1.1552 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 12254.154 | 1.2718 | 1.3178 | 1.6307 | |
| MCF 10F | NM | - | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 12254.154 | 1.3541 | 1.4086 | 1.6307 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10817.154 | 0.9914 | 0.9881 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10817.154 | 0.9894 | 0.9854 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10817.154 | 0.9987 | 0.9982 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10817.154 | 0.9835 | 0.9773 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10817.154 | 1.0145 | 1.0198 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10817.154 | 1.0301 | 1.0412 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10817.154 | 1.0046 | 1.0063 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10817.154 | 1.0840 | 1.1139 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10817.154 | 1.0238 | 1.0326 | 1.4551 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000171 | uM | 12365.167 | 0.9956 | 0.9957 | 2.0273 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.000853 | uM | 12365.167 | 1.0773 | 1.0749 | 2.0273 | |
| MCF12A | NM | Basal B | FTase Inhibitor I | Ftase | MAPK | 0.00427 | uM | 12365.167 | 0.9725 | 0.9727 | 2.0273 |