Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7489.074 | 0.9341 | 0.9379 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7489.074 | 0.9149 | 0.9194 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7489.074 | 0.8467 | 0.8518 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7489.074 | 0.6583 | 0.6483 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7489.074 | 0.4948 | 0.4444 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7489.074 | 0.4126 | 0.3279 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7489.074 | 0.2988 | 0.1437 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7489.074 | 0.1012 | -0.3067 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7489.074 | 0.0945 | -0.3284 | 2.1617 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7490.074 | 0.9053 | 0.9274 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7490.074 | 0.8871 | 0.9130 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7490.074 | 0.8584 | 0.8897 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7490.074 | 0.7282 | 0.7777 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7490.074 | 0.5151 | 0.5630 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7490.074 | 0.3963 | 0.4179 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7490.074 | 0.2683 | 0.2266 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7490.074 | 0.1369 | -0.0447 | 2.6912 | |
| MCF12A | NM | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7490.074 | 0.1211 | -0.0873 | 2.6912 | |
| MCF7 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7492.074 | 1.0529 | 1.0738 | 1.4222 | |
| MCF7 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7492.074 | 0.9621 | 0.9464 | 1.4222 | |
| MCF7 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7492.074 | 0.9760 | 0.9662 | 1.4222 | |
| MCF7 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7492.074 | 0.9928 | 0.9899 | 1.4222 | |
| MCF7 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7492.074 | 0.9156 | 0.8798 | 1.4222 | |
| MCF7 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7492.074 | 0.8578 | 0.7955 | 1.4222 | |
| MCF7 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7492.074 | 0.6993 | 0.5552 | 1.4222 |