Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1419 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 12001.164 | 0.6367 | -0.2362 | 0.4690 | |
HCC1419 | HER2amp | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 12001.164 | 0.4377 | -0.6565 | 0.4690 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000171 | uM | 11936.164 | 0.9602 | 0.9090 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.000853 | uM | 11936.164 | 0.9456 | 0.8757 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.00427 | uM | 11936.164 | 0.9277 | 0.8351 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.0213 | uM | 11936.164 | 0.9040 | 0.7812 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.107 | uM | 11936.164 | 0.8242 | 0.6021 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 0.533 | uM | 11936.164 | 0.7623 | 0.4649 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 2.67 | uM | 11936.164 | 0.7509 | 0.4398 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 13.3 | uM | 11936.164 | 0.7187 | 0.3691 | 0.8717 | |
HCC1428 | HR+ | Luminal | Everolimus | MTOR | MTOR | 66.7 | uM | 11936.164 | 0.0356 | -0.9565 | 0.8717 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.000171 | uM | 10872.156 | 0.9368 | 0.9150 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.000853 | uM | 10872.156 | 0.9242 | 0.8978 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.00427 | uM | 10872.156 | 0.8152 | 0.7457 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.0213 | uM | 10872.156 | 0.7471 | 0.6474 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.107 | uM | 10872.156 | 0.6399 | 0.4859 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.533 | uM | 10872.156 | 0.6496 | 0.5010 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 2.67 | uM | 10872.156 | 0.6631 | 0.5215 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 13.3 | uM | 10872.156 | 0.6165 | 0.4495 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 66.7 | uM | 10872.156 | 0.0234 | -0.8357 | 1.5028 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.000171 | uM | 12523.164 | 0.9588 | 0.9002 | 0.8230 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.000853 | uM | 12523.164 | 0.9224 | 0.8130 | 0.8230 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.00427 | uM | 12523.164 | 0.8517 | 0.6455 | 0.8230 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.0213 | uM | 12523.164 | 0.7639 | 0.4419 | 0.8230 | |
HCC1569 | HER2amp | Basal A | Everolimus | MTOR | MTOR | 0.107 | uM | 12523.164 | 0.7117 | 0.3230 | 0.8230 |