Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
HCC1419
HER2amp
Luminal
Everolimus
MTOR
MTOR
13.3
uM
12001.164
0.6367 -0.2362 0.4690
HCC1419
HER2amp
Luminal
Everolimus
MTOR
MTOR
66.7
uM
12001.164
0.4377 -0.6565 0.4690
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
0.000171
uM
11936.164
0.9602 0.9090 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
0.000853
uM
11936.164
0.9456 0.8757 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
0.00427
uM
11936.164
0.9277 0.8351 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
0.0213
uM
11936.164
0.9040 0.7812 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
0.107
uM
11936.164
0.8242 0.6021 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
0.533
uM
11936.164
0.7623 0.4649 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
2.67
uM
11936.164
0.7509 0.4398 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
13.3
uM
11936.164
0.7187 0.3691 0.8717
HCC1428
HR+
Luminal
Everolimus
MTOR
MTOR
66.7
uM
11936.164
0.0356 -0.9565 0.8717
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.000171
uM
10872.156
0.9368 0.9150 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.000853
uM
10872.156
0.9242 0.8978 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.00427
uM
10872.156
0.8152 0.7457 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.0213
uM
10872.156
0.7471 0.6474 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.107
uM
10872.156
0.6399 0.4859 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.533
uM
10872.156
0.6496 0.5010 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
2.67
uM
10872.156
0.6631 0.5215 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
13.3
uM
10872.156
0.6165 0.4495 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
66.7
uM
10872.156
0.0234 -0.8357 1.5028
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.000171
uM
12523.164
0.9588 0.9002 0.8230
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.000853
uM
12523.164
0.9224 0.8130 0.8230
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.00427
uM
12523.164
0.8517 0.6455 0.8230
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.0213
uM
12523.164
0.7639 0.4419 0.8230
HCC1569
HER2amp
Basal A
Everolimus
MTOR
MTOR
0.107
uM
12523.164
0.7117 0.3230 0.8230