Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10520.142	0.9491	0.9674	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10520.142	0.9026	0.9365	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10520.142	0.9179	0.9468	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10520.142	0.0012	-0.7591	3.1766
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	11057.154	0.9521	0.9747	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	11057.154	1.0458	1.0234	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	11057.154	0.9839	0.9916	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	11057.154	0.9127	0.9531	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	11057.154	0.9933	0.9965	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	0.267	uM	11057.154	0.9303	0.9628	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	1.33	uM	11057.154	1.0119	1.0062	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	6.67	uM	11057.154	0.5673	0.7262	3.8498
SUM159PT	TNBC	Basal B	FTase Inhibitor I	Ftase	MAPK	33.3	uM	11057.154	0.0032	-0.5505	3.8498
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	12269.154	0.6759	0.3518	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	12269.154	0.9909	0.9818	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	12269.154	0.6791	0.3581	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	12269.154	0.9279	0.8558	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	12269.154	0.6981	0.3962	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	12269.154	0.9292	0.8583	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	12269.154	0.6666	0.3332	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	12269.154	0.9168	0.8335	0.9999
SUM185PE	TNBC	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	12269.154	0.5472	0.0944	0.9999
SUM225CWN	HER2amp	Basal A	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10579.142	0.9492	0.9025	1.0435
SUM225CWN	HER2amp	Basal A	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10579.142	0.9659	0.9346	1.0435
SUM225CWN	HER2amp	Basal A	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10579.142	0.9774	0.9566	1.0435

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)