Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7829.017 | 0.9770 | 0.9764 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7829.017 | 0.8905 | 0.8849 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7829.017 | 0.4122 | 0.2715 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7829.017 | 0.0341 | -0.6445 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7829.017 | 0.0159 | -0.7588 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7829.017 | 0.0216 | -0.7184 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7829.017 | 0.0033 | -0.8928 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7830.017 | 0.9135 | 0.8978 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7830.017 | 0.9612 | 0.9546 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7830.017 | 0.9340 | 0.9224 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7830.017 | 0.7711 | 0.7202 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7830.017 | 0.5751 | 0.4512 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7830.017 | 0.0826 | -0.5290 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7830.017 | 0.0416 | -0.6836 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7830.017 | 0.0457 | -0.6656 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7830.017 | 0.0002 | -0.9837 | 1.7247 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7832.017 | 0.9986 | 0.9980 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7832.017 | 0.9862 | 0.9794 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7832.017 | 0.9604 | 0.9406 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7832.017 | 0.9556 | 0.9333 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7832.017 | 0.5897 | 0.3486 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7832.017 | 0.1851 | -0.4318 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7832.017 | 0.1452 | -0.5259 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7832.017 | 0.0929 | -0.6602 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7832.017 | 0.0002 | -0.9960 | 1.3404 |