Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7932.017 | 0.1980 | -0.5590 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7932.017 | 0.4129 | -0.1242 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7932.017 | 0.3583 | -0.2328 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7932.017 | 0.0031 | -0.9909 | 1.0712 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9972.017 | 1.0082 | 1.0141 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9972.017 | 0.9842 | 0.9729 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9972.017 | 0.9772 | 0.9608 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9972.017 | 0.8197 | 0.6866 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9972.017 | 0.5394 | 0.1782 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9972.017 | 0.1893 | -0.5198 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9972.017 | 0.1919 | -0.5141 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9972.017 | 0.1757 | -0.5496 | 1.1666 | |
| ZR75B | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9972.017 | 0.0008 | -0.9953 | 1.1666 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5895.091 | 1.0990 | 1.1676 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5895.091 | 1.0122 | 1.0208 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5895.091 | 1.0872 | 1.1478 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5895.091 | 1.0707 | 1.1199 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 0.107 | uM | 5895.091 | 0.9509 | 0.9160 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 0.533 | uM | 5895.091 | 0.3959 | -0.0923 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 2.67 | uM | 5895.091 | 0.3748 | -0.1338 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 13.3 | uM | 5895.091 | 0.3750 | -0.1333 | 1.1729 | |
| 184A1 | NM | Basal | Erlotinib | EGFR | ErbB | 66.7 | uM | 5895.091 | 0.3528 | -0.1773 | 1.1729 | |
| 184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5896.091 | 0.9709 | 0.9610 | 1.4988 | |
| 184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5896.091 | 0.9361 | 0.9138 | 1.4988 | |
| 184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5896.091 | 0.9137 | 0.8831 | 1.4988 |