Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5896.091 | 0.9335 | 0.9102 | 1.4988 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.107 | uM | 5896.091 | 0.7330 | 0.6257 | 1.4988 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.533 | uM | 5896.091 | 0.5150 | 0.2846 | 1.4988 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 2.67 | uM | 5896.091 | 0.4947 | 0.2504 | 1.4988 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 13.3 | uM | 5896.091 | 0.4650 | 0.1998 | 1.4988 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 66.7 | uM | 5896.091 | 0.4081 | 0.0999 | 1.4988 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5897.091 | 0.9741 | 0.9577 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5897.091 | 1.0193 | 1.0313 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5897.091 | 1.0146 | 1.0237 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5897.091 | 0.9809 | 0.9688 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.107 | uM | 5897.091 | 0.9768 | 0.9621 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 0.533 | uM | 5897.091 | 0.7470 | 0.5777 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 2.67 | uM | 5897.091 | 0.6579 | 0.4229 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 13.3 | uM | 5897.091 | 0.4764 | 0.0943 | 1.2296 | |
184B5 | NM | Basal | Erlotinib | EGFR | ErbB | 66.7 | uM | 5897.091 | 0.4447 | 0.0348 | 1.2296 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5898.091 | 1.0117 | 1.0380 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 5898.091 | 0.9467 | 0.8298 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 5898.091 | 0.9404 | 0.8101 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 5898.091 | 0.9549 | 0.8557 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 5898.091 | 0.9551 | 0.8561 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 5898.091 | 0.8748 | 0.6097 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 5898.091 | 0.8616 | 0.5704 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 5898.091 | 0.8116 | 0.4251 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 5898.091 | 0.8510 | 0.5391 | 0.6159 | |
600MPE | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 5899.09 | 0.9679 | 0.9382 | 1.0401 |