Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 5911.084 | 0.9821 | 0.9650 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 5911.084 | 1.0071 | 1.0139 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 5911.084 | 0.9838 | 0.9685 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 5911.084 | 0.9433 | 0.8894 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 5911.084 | 0.7180 | 0.4481 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 5911.084 | 0.0062 | -0.9858 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 5911.084 | 0.0104 | -0.9767 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 5911.084 | 0.0059 | -0.9865 | 1.0262 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 5912.084 | 1.0263 | 1.0479 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 5912.084 | 1.0127 | 1.0232 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 5912.084 | 0.9965 | 0.9936 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 5912.084 | 1.0335 | 1.0609 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 5912.084 | 0.9558 | 0.9193 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 5912.084 | 0.7169 | 0.4764 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 5912.084 | 0.0094 | -0.9717 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 5912.084 | 0.0090 | -0.9728 | 1.0966 | |
| CAMA-1 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 5912.084 | 0.0084 | -0.9745 | 1.0966 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7429.084 | 0.9963 | 0.9967 | 2.2510 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7429.084 | 1.0619 | 1.0541 | 2.2510 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7429.084 | 1.0003 | 1.0002 | 2.2510 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7429.084 | 1.0106 | 1.0094 | 2.2510 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7429.084 | 1.0049 | 1.0043 | 2.2510 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7429.084 | 0.9138 | 0.9215 | 2.2510 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7429.084 | 0.0296 | -0.5812 | 2.2510 | |
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7429.084 | 0.0093 | -0.7493 | 2.2510 |