Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7429.084 | 0.0078 | -0.7688 | 2.2510 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7430.085 | 1.0265 | 1.0269 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7430.085 | 1.0684 | 1.0687 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7430.085 | 1.0424 | 1.0429 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7430.085 | 0.9857 | 0.9854 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7430.085 | 0.8939 | 0.8887 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7430.085 | 0.6676 | 0.6272 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7430.085 | 0.0235 | -0.7054 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7430.085 | 0.0093 | -0.8166 | 1.9592 | |
| HCC1143 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7430.085 | 0.0036 | -0.8868 | 1.9592 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7432.084 | 1.1374 | 1.3254 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7432.084 | 1.0715 | 1.1685 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7432.084 | 1.0045 | 1.0106 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7432.084 | 0.7655 | 0.4625 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7432.084 | 0.1124 | -0.8455 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7432.084 | 0.0073 | -0.9937 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7432.084 | 0.0044 | -0.9965 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7432.084 | 0.0108 | -0.9900 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7432.084 | 0.0003 | -0.9998 | 0.8538 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7433.084 | 0.9925 | 0.9853 | 1.0291 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7433.084 | 0.9999 | 0.9999 | 1.0291 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7433.084 | 1.0035 | 1.0068 | 1.0291 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7433.084 | 0.8989 | 0.8033 | 1.0291 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7433.084 | 0.3040 | -0.3712 | 1.0291 | |
| HCC1187 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7433.084 | 0.0068 | -0.9843 | 1.0291 |