Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7494.084 | 0.6908 | 0.3953 | 1.0275 | |
| MDA-MB-134-VI | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7494.084 | 0.0819 | -0.8248 | 1.0275 | |
| MDA-MB-134-VI | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7494.084 | 0.0108 | -0.9755 | 1.0275 | |
| MDA-MB-134-VI | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7494.084 | 0.0056 | -0.9871 | 1.0275 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7496.085 | 1.0001 | 1.0002 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7496.085 | 0.9178 | 0.8466 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7496.085 | 0.9639 | 0.9327 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7496.085 | 0.9103 | 0.8325 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7496.085 | 0.8482 | 0.7160 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7496.085 | 0.6207 | 0.2832 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7496.085 | 0.0042 | -0.9876 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7496.085 | 0.0071 | -0.9800 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7496.085 | 0.0045 | -0.9868 | 1.0748 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7498.084 | 0.9812 | 0.9679 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7498.084 | 0.9293 | 0.8790 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7498.084 | 1.0351 | 1.0595 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7498.084 | 0.9560 | 0.9249 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7498.084 | 0.9412 | 0.8995 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7498.084 | 0.7968 | 0.6483 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7498.084 | 0.0085 | -0.9654 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7498.084 | 0.0103 | -0.9593 | 1.1749 | |
| MDA-MB-157 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7498.084 | 0.0028 | -0.9867 | 1.1749 | |
| MDA-MB-175-VII | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7499.084 | 0.9956 | 0.9891 | 0.7991 | |
| MDA-MB-175-VII | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7499.084 | 0.9490 | 0.8732 | 0.7991 | |
| MDA-MB-175-VII | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7499.084 | 0.9833 | 0.9584 | 0.7991 |