Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 7470.091 | 0.8090 | 0.6101 | 0.9773 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 7470.091 | 0.8211 | 0.6348 | 0.9773 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 7470.091 | 0.4787 | -0.0587 | 0.9773 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 7470.091 | 0.3990 | -0.2188 | 0.9773 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7471.092 | 0.5274 | -0.6187 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7471.092 | 0.7558 | -0.0315 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7471.092 | 1.2393 | 2.4867 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7471.092 | 0.5547 | -0.5655 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7471.092 | 0.9240 | 0.6295 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.267 | uM | 7471.092 | 0.9300 | 0.6574 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 1.33 | uM | 7471.092 | 0.9743 | 0.8693 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 6.67 | uM | 7471.092 | 0.7007 | -0.2040 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 33.3 | uM | 7471.092 | 0.6565 | -0.3277 | 0.3860 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7472.092 | 1.2152 | 1.3324 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7472.092 | 1.2340 | 1.3608 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7472.092 | 1.1048 | 1.1636 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7472.092 | 1.3127 | 1.4788 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7472.092 | 1.0981 | 1.1532 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.267 | uM | 7472.092 | 1.1643 | 1.2550 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 1.33 | uM | 7472.092 | 1.2704 | 1.4155 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 6.67 | uM | 7472.092 | 1.0110 | 1.0174 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 33.3 | uM | 7472.092 | 2.0320 | 2.4990 | 1.2676 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7473.091 | 1.3541 | 1.2780 | 2.3297 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7473.091 | 1.2781 | 1.2221 | 2.3297 | |
| Hs 578T | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7473.091 | 1.2402 | 1.1936 | 2.3297 |