Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7465.092 | 1.0456 | 1.0754 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7465.092 | 0.9585 | 0.9309 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7465.092 | 0.9581 | 0.9302 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7465.092 | 0.9575 | 0.9292 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7465.092 | 0.9274 | 0.8787 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.267 | uM | 7465.092 | 0.8989 | 0.8308 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 1.33 | uM | 7465.092 | 0.9204 | 0.8670 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 6.67 | uM | 7465.092 | 0.8230 | 0.7015 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 33.3 | uM | 7465.092 | 0.6013 | 0.3115 | 1.2055 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7466.092 | 1.0079 | 1.0173 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7466.092 | 0.9599 | 0.9127 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7466.092 | 0.9785 | 0.9532 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7466.092 | 0.9851 | 0.9675 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7466.092 | 1.0310 | 1.0678 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.267 | uM | 7466.092 | 1.0038 | 1.0082 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 1.33 | uM | 7466.092 | 1.0016 | 1.0035 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 6.67 | uM | 7466.092 | 1.0102 | 1.0222 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 33.3 | uM | 7466.092 | 0.6911 | 0.3360 | 0.9158 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7467.091 | 0.9829 | 0.9737 | 1.2996 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7467.091 | 0.9477 | 0.9190 | 1.2996 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7467.091 | 1.0004 | 1.0006 | 1.2996 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7467.091 | 0.9599 | 0.9380 | 1.2996 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 7467.091 | 0.9646 | 0.9452 | 1.2996 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 7467.091 | 1.0148 | 1.0228 | 1.2996 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 7467.091 | 0.9521 | 0.9259 | 1.2996 |