Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7462.092 | 1.0015 | 1.0069 | 0.4336 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7462.092 | 1.0069 | 1.0322 | 0.4336 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7462.092 | 1.0201 | 1.0939 | 0.4336 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.267 | uM | 7462.092 | 0.9344 | 0.7101 | 0.4336 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 1.33 | uM | 7462.092 | 0.9702 | 0.8650 | 0.4336 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 6.67 | uM | 7462.092 | 0.9461 | 0.7603 | 0.4336 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 7462.092 | 0.8758 | 0.4732 | 0.4336 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7463.09 | 0.9936 | 0.9767 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7463.09 | 0.9336 | 0.7645 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7463.09 | 1.0020 | 1.0073 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7463.09 | 0.9755 | 0.9117 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7463.09 | 0.9675 | 0.8831 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7463.09 | 0.9033 | 0.6612 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7463.09 | 0.9026 | 0.6589 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7463.09 | 0.8600 | 0.5191 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7463.09 | 0.8149 | 0.3770 | 0.5483 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7464.09 | 0.9914 | 0.9655 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7464.09 | 1.0555 | 1.2304 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7464.09 | 1.0275 | 1.1126 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7464.09 | 0.9978 | 0.9913 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7464.09 | 0.9692 | 0.8778 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7464.09 | 0.9971 | 0.9882 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7464.09 | 1.0510 | 1.2110 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7464.09 | 0.9206 | 0.6925 | 0.4958 | |
| HCC2185 | TNBC | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7464.09 | 0.8348 | 0.3895 | 0.4958 |