Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7487.084 | 0.9606 | 0.9409 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7487.084 | 1.0329 | 1.0489 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7487.084 | 0.9942 | 0.9913 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7487.084 | 0.9520 | 0.9279 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7487.084 | 0.8831 | 0.8228 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7487.084 | 0.7112 | 0.5507 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7487.084 | 0.0500 | -0.7862 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7487.084 | 0.0069 | -0.9511 | 1.3396 | |
| MCF 10F | NM | - | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7487.084 | 0.0019 | -0.9814 | 1.3396 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7489.084 | 1.0206 | 1.0202 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7489.084 | 0.9934 | 0.9935 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7489.084 | 0.9767 | 0.9769 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7489.084 | 1.0295 | 1.0288 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7489.084 | 0.9665 | 0.9666 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7489.084 | 0.7114 | 0.6908 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7489.084 | 0.0242 | -0.6807 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7489.084 | 0.0102 | -0.7914 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7489.084 | 0.0059 | -0.8411 | 2.0279 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7490.085 | 1.0107 | 1.0083 | 2.5778 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7490.085 | 0.9427 | 0.9548 | 2.5778 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7490.085 | 0.9947 | 0.9959 | 2.5778 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7490.085 | 1.0113 | 1.0087 | 2.5778 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7490.085 | 0.9430 | 0.9550 | 2.5778 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7490.085 | 0.6847 | 0.7267 | 2.5778 | |
| MCF12A | NM | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7490.085 | 0.1492 | -0.0440 | 2.5778 |