Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7443.084 | 0.9825 | 0.9645 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7443.084 | 0.9643 | 0.9276 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7443.084 | 0.6220 | 0.2368 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7443.084 | 0.0092 | -0.9826 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7443.084 | 0.0077 | -0.9854 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7443.084 | 0.0116 | -0.9781 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7443.084 | 0.0059 | -0.9890 | 0.9878 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7444.084 | 0.9866 | 0.9691 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7444.084 | 1.0008 | 1.0019 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7444.084 | 0.9691 | 0.9287 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7444.084 | 0.9726 | 0.9368 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7444.084 | 0.4768 | -0.1507 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7444.084 | 0.0145 | -0.9851 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7444.084 | 0.0105 | -0.9897 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7444.084 | 0.0153 | -0.9841 | 0.8647 | |
| HCC1428 | HR+ | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7444.084 | 0.0053 | -0.9954 | 0.8647 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7447.084 | 1.0195 | 1.0257 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7447.084 | 1.0310 | 1.0407 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7447.084 | 1.0421 | 1.0552 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7447.084 | 0.9669 | 0.9560 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7447.084 | 0.9638 | 0.9519 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7447.084 | 0.7540 | 0.6600 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7447.084 | 0.0156 | -0.8715 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7447.084 | 0.0094 | -0.9080 | 1.5152 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7447.084 | 0.0031 | -0.9554 | 1.5152 |