Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7845.016 | 0.9669 | 0.8524 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7845.016 | 0.9694 | 0.8632 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7845.016 | 0.9304 | 0.6972 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7845.016 | 1.0187 | 1.0863 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7845.016 | 0.9494 | 0.7772 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7845.016 | 0.9310 | 0.6995 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7845.016 | 0.9755 | 0.8900 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7845.016 | 0.9379 | 0.7285 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7845.016 | 0.6045 | -0.3643 | 0.4392 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7846.016 | 1.0210 | 1.1307 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7846.016 | 1.0047 | 1.0289 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7846.016 | 0.9939 | 0.9632 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7846.016 | 1.0203 | 1.1266 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7846.016 | 0.9939 | 0.9632 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7846.016 | 0.9404 | 0.6580 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7846.016 | 0.9820 | 0.8919 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7846.016 | 0.9384 | 0.6476 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7846.016 | 0.5038 | -0.7529 | 0.3279 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7848.016 | 1.0023 | 1.0095 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7848.016 | 1.0850 | 1.3691 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7848.016 | 0.9747 | 0.8963 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7848.016 | 1.0143 | 1.0599 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7848.016 | 1.0569 | 1.2436 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7848.016 | 1.0263 | 1.1107 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7848.016 | 0.9723 | 0.8866 | 0.4818 |