Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7814.016 | 0.9871 | 0.9700 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7814.016 | 0.9724 | 0.9361 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7814.016 | 0.9823 | 0.9590 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7814.016 | 0.9507 | 0.8860 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7814.016 | 0.9225 | 0.8213 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7814.016 | 0.8016 | 0.5475 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7814.016 | 0.6076 | 0.1222 | 0.8623 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7815.016 | 1.0127 | 1.0584 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7815.016 | 1.0683 | 1.3267 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7815.016 | 0.9996 | 0.9983 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7815.016 | 1.0480 | 1.2264 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7815.016 | 1.0299 | 1.1393 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7815.016 | 1.0755 | 1.3626 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7815.016 | 1.0046 | 1.0210 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7815.016 | 1.0534 | 1.2531 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7815.016 | 0.7844 | 0.1471 | 0.4370 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7816.016 | 0.9812 | 0.9663 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7816.016 | 0.9629 | 0.9336 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7816.016 | 1.0458 | 1.0818 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7816.016 | 0.9656 | 0.9384 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7816.016 | 0.9488 | 0.9082 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 0.267 | uM | 7816.016 | 0.9153 | 0.8477 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 1.33 | uM | 7816.016 | 0.9483 | 0.9074 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 6.67 | uM | 7816.016 | 0.9016 | 0.8230 | 1.1183 | |
| HCC1395 | TNBC | Basal B | Gefitinib | EGFR | ErbB | 33.3 | uM | 7816.016 | 0.3235 | -0.2709 | 1.1183 |