Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
ZR-75-1
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.107
uM
12003.167
 0.8569 0.7414 1.1158
ZR-75-1
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.533
uM
12003.167
 0.8827 0.7885 1.1158
ZR-75-1
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
2.67
uM
12003.167
 0.8838 0.7903 1.1158
ZR-75-1
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
13.3
uM
12003.167
 0.8574 0.7423 1.1158
ZR-75-1
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
66.7
uM
12003.167
 0.8508 0.7304 1.1158
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.0000853
uM
11939.154
 0.9301 0.9176 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.000427
uM
11939.154
 0.9058 0.8885 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.00213
uM
11939.154
 0.9723 0.9677 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.0107
uM
11939.154
 0.8993 0.8807 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.0533
uM
11939.154
 0.9435 0.9337 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
0.267
uM
11939.154
 0.8805 0.8577 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
1.33
uM
11939.154
 0.9550 0.9474 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
6.67
uM
11939.154
 0.8862 0.8647 1.7246
ZR75B
HR+
Luminal
 FTase Inhibitor I
Ftase
MAPK
33.3
uM
11939.154
 0.9173 0.9024 1.7246
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
0.0000853
uM
9047.132
 0.9508 0.8605 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
0.000427
uM
9047.132
 0.9756 0.9306 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
0.00213
uM
9047.132
 0.8265 0.5226 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
0.0107
uM
9047.132
 0.7299 0.2744 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
0.0533
uM
9047.132
 0.6561 0.0939 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
0.267
uM
9047.132
 0.9837 0.9533 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
1.33
uM
9047.132
 0.8476 0.5783 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
6.67
uM
9047.132
 0.7955 0.4414 0.6985
184A1
NM
Basal
 Gefitinib
EGFR
ErbB
33.3
uM
9047.132
 0.8234 0.5144 0.6985
184B5
NM
Basal
 Gefitinib
EGFR
ErbB
0.0000853
uM
9095.049
 1.0384 1.0684 1.1202
184B5
NM
Basal
 Gefitinib
EGFR
ErbB
0.000427
uM
9095.049
 1.0055 1.0098 1.1202