Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	12126.154	0.9764	0.9221	0.6012
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	12126.154	0.9259	0.7595	0.6012
MDA-MB-175-VII	HR+	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	12126.154	0.8928	0.6563	0.6012
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10643.142	0.9733	0.8978	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10643.142	1.0120	1.0466	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10643.142	0.9548	0.8289	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10643.142	0.9401	0.7745	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10643.142	1.0448	1.1770	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10643.142	0.9899	0.9610	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10643.142	0.9879	0.9535	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10643.142	0.9580	0.8407	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10643.142	1.0211	1.0826	0.5166
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0000853	uM	10999.154	0.9287	0.8003	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000427	uM	10999.154	1.0254	1.0727	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00213	uM	10999.154	0.9768	0.9342	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0107	uM	10999.154	0.9490	0.8564	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0533	uM	10999.154	1.0309	1.0886	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.267	uM	10999.154	0.9616	0.8916	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	1.33	uM	10999.154	0.9711	0.9182	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	6.67	uM	10999.154	0.9140	0.7597	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	33.3	uM	10999.154	1.0607	1.1750	0.7027
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000171	uM	12379.167	1.0053	1.0204	0.5212
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.000853	uM	12379.167	1.0496	1.1949	0.5212
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.00427	uM	12379.167	0.9857	0.9454	0.5212
MDA-MB-361	HER2amp	Luminal	FTase Inhibitor I	Ftase	MAPK	0.0213	uM	12379.167	0.9792	0.9210	0.5212

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)