Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7848.016 | 0.9742 | 0.8944 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7848.016 | 0.9244 | 0.6991 | 0.4818 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7849.016 | 1.0313 | 1.1889 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7849.016 | 0.9961 | 0.9772 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7849.016 | 0.9745 | 0.8545 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7849.016 | 1.0752 | 1.4723 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7849.016 | 0.9898 | 0.9407 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7849.016 | 1.0095 | 1.0560 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7849.016 | 0.9790 | 0.8799 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7849.016 | 0.9215 | 0.5748 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7849.016 | 0.6700 | -0.3800 | 0.3419 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9420.132 | 1.0775 | 1.5064 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9420.132 | 1.0714 | 1.4635 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9420.132 | 1.0752 | 1.4899 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9420.132 | 0.8262 | 0.1231 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9420.132 | 1.0052 | 1.0317 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9420.132 | 1.0052 | 1.0313 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9420.132 | 1.0394 | 1.2479 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9420.132 | 0.9048 | 0.4783 | 0.3309 | |
| HCC2185 | TNBC | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9420.132 | 1.0065 | 1.0397 | 0.3309 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7853.016 | 1.0462 | 1.0567 | 1.6178 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7853.016 | 0.9645 | 0.9557 | 1.6178 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7853.016 | 0.9786 | 0.9734 | 1.6178 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7853.016 | 1.0199 | 1.0245 | 1.6178 | |
| HCC3153 | TNBC | Basal A | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7853.016 | 0.9837 | 0.9798 | 1.6178 |