Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7448.084 | 1.0239 | 1.0168 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7448.084 | 1.0048 | 1.0034 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7448.084 | 1.0088 | 1.0062 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7448.084 | 0.9964 | 0.9974 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7448.084 | 1.0024 | 1.0017 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7448.084 | 0.8416 | 0.8814 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7448.084 | 0.1127 | -0.0771 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7448.084 | 0.0128 | -0.5730 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7448.084 | 0.0065 | -0.6649 | 2.8225 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7449.084 | 0.9541 | 0.9566 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7449.084 | 0.9425 | 0.9454 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7449.084 | 0.9534 | 0.9559 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7449.084 | 0.9595 | 0.9618 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7449.084 | 0.9416 | 0.9445 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7449.084 | 0.7951 | 0.7968 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7449.084 | 0.1117 | -0.2816 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7449.084 | 0.0112 | -0.7547 | 2.1410 | |
| HCC1569 | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7449.084 | 0.0051 | -0.8295 | 2.1410 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7450.084 | 0.9999 | 0.9999 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7450.084 | 1.1049 | 1.0870 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7450.084 | 0.9590 | 0.9646 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7450.084 | 1.0535 | 1.0450 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7450.084 | 0.9689 | 0.9732 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7450.084 | 0.6309 | 0.6431 | 2.3432 | |
| HCC1806 | TNBC | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7450.084 | 0.0222 | -0.6061 | 2.3432 |