Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7808.043 | 0.0401 | -0.4794 | 2.3907 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7808.043 | 0.0022 | -0.8458 | 2.3907 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7808.043 | 0.0006 | -0.9110 | 2.3907 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7808.043 | 0.0869 | -0.2801 | 2.3907 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7808.043 | 0.1187 | -0.1800 | 2.3907 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 9226.034 | 1.0374 | 1.0282 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 9226.034 | 0.9734 | 0.9795 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 9226.034 | 1.0011 | 1.0008 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 9226.034 | 0.8441 | 0.8746 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.138 | uM | 9226.034 | 0.1004 | -0.1689 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.69 | uM | 9226.034 | 0.0114 | -0.6379 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 3.45 | uM | 9226.034 | 0.0070 | -0.7000 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 17.2 | uM | 9226.034 | 0.0083 | -0.6790 | 2.6175 | |
| HBL-100 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 86.2 | uM | 9226.034 | 0.0019 | -0.8190 | 2.6175 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7810.007 | 1.0837 | 1.1744 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7810.007 | 1.0014 | 1.0028 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7810.007 | 1.0735 | 1.1531 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7810.007 | 1.0217 | 1.0452 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7810.007 | 1.0355 | 1.0739 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7810.007 | 0.3578 | -0.3132 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7810.007 | 0.1392 | -0.7426 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7810.007 | 0.0955 | -0.8262 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7810.007 | 0.0267 | -0.9538 | 0.9616 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9233.121 | 1.0436 | 1.0922 | 0.9468 | |
| HCC1143 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9233.121 | 0.9691 | 0.9348 | 0.9468 |