Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9897.002 | 0.4963 | -0.6427 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9897.002 | 0.5602 | -0.5189 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9897.002 | 0.6538 | -0.2964 | 0.4068 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12720.002 | 1.0820 | 1.1580 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12720.002 | 1.0326 | 1.0629 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12720.002 | 1.0209 | 1.0404 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12720.002 | 0.7575 | 0.5301 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 12720.002 | 0.5342 | 0.0924 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 12720.002 | 0.4948 | 0.0145 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 12720.002 | 0.5085 | 0.0417 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 12720.002 | 0.5129 | 0.0504 | 1.0368 | |
| T47D | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 12720.002 | 0.5157 | 0.0560 | 1.0368 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13070.002 | 1.0635 | 1.1624 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13070.002 | 1.0122 | 1.0309 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13070.002 | 0.9909 | 0.9769 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13070.002 | 0.9698 | 0.9238 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.016 | uM | 13070.002 | 0.7157 | 0.3088 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.08 | uM | 13070.002 | 0.4461 | -0.2811 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.4 | uM | 13070.002 | 0.4266 | -0.3208 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 2 | uM | 13070.002 | 0.4086 | -0.3570 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Docetaxel | TUBB | TUBB | 10 | uM | 13070.002 | 0.4627 | -0.2471 | 0.7888 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9913.002 | 1.0353 | 1.1060 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9913.002 | 1.0379 | 1.1138 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9913.002 | 0.9695 | 0.9099 | 0.6723 | |
| UACC-812 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9913.002 | 0.8527 | 0.5779 | 0.6723 |