Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00213 | uM | 10381.092 | 0.9767 | 0.9669 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0107 | uM | 10381.092 | 0.9442 | 0.9204 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0533 | uM | 10381.092 | 0.9627 | 0.9469 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.267 | uM | 10381.092 | 0.8694 | 0.8115 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 1.33 | uM | 10381.092 | 0.8786 | 0.8251 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 6.67 | uM | 10381.092 | 0.8176 | 0.7345 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 33.3 | uM | 10381.092 | 0.5837 | 0.3667 | 1.4137 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7530.091 | 1.0558 | 1.0529 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7530.091 | 0.9986 | 0.9987 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7530.091 | 1.0513 | 1.0487 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7530.091 | 0.9761 | 0.9769 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7530.091 | 0.7873 | 0.7828 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7530.091 | 0.6148 | 0.5829 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7530.091 | 0.6521 | 0.6283 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7530.091 | 0.5306 | 0.4745 | 2.0794 | |
| SUM149PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7530.091 | 0.3858 | 0.2650 | 2.0794 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7531.091 | 1.0572 | 1.0338 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7531.091 | 1.0533 | 1.0316 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7531.091 | 1.0362 | 1.0216 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7531.091 | 1.0250 | 1.0150 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7531.091 | 0.9903 | 0.9941 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7531.091 | 0.9473 | 0.9676 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7531.091 | 0.9033 | 0.9396 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7531.091 | 0.5135 | 0.6356 | 3.3140 | |
| SUM159PT | TNBC | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7531.091 | 0.4188 | 0.5380 | 3.3140 |