Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Erlotinib | EGFR | ErbB | 0.107 | uM | 7487.09 | 0.8159 | 0.7498 | 1.5226 | |
| MCF 10F | NM | - | Erlotinib | EGFR | ErbB | 0.533 | uM | 7487.09 | 0.3922 | 0.0816 | 1.5226 | |
| MCF 10F | NM | - | Erlotinib | EGFR | ErbB | 2.67 | uM | 7487.09 | 0.3112 | -0.0709 | 1.5226 | |
| MCF 10F | NM | - | Erlotinib | EGFR | ErbB | 13.3 | uM | 7487.09 | 0.2668 | -0.1603 | 1.5226 | |
| MCF 10F | NM | - | Erlotinib | EGFR | ErbB | 66.7 | uM | 7487.09 | 0.2264 | -0.2461 | 1.5226 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7489.09 | 1.0852 | 1.0844 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7489.09 | 0.9808 | 0.9805 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7489.09 | 1.0825 | 1.0818 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7489.09 | 1.1402 | 1.1371 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7489.09 | 0.8967 | 0.8927 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7489.09 | 0.5681 | 0.5029 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7489.09 | 0.3666 | 0.2045 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7489.09 | 0.2621 | 0.0166 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7489.09 | 0.2188 | -0.0720 | 1.9790 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7490.091 | 0.9533 | 0.9629 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7490.091 | 0.9930 | 0.9945 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7490.091 | 0.9795 | 0.9838 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7490.091 | 0.9285 | 0.9428 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7490.091 | 0.8402 | 0.8682 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7490.091 | 0.5271 | 0.5565 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7490.091 | 0.4328 | 0.4410 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7490.091 | 0.1517 | -0.0440 | 2.5547 | |
| MCF12A | NM | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7490.091 | 0.1362 | -0.0836 | 2.5547 | |
| MCF7 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7492.091 | 0.9607 | 0.9456 | 1.4539 | |
| MCF7 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7492.091 | 0.9581 | 0.9420 | 1.4539 |