Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7528.084 | 0.9934 | 0.9872 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7528.084 | 1.0029 | 1.0056 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7528.084 | 0.9272 | 0.8577 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7528.084 | 0.8524 | 0.7114 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7528.084 | 0.3427 | -0.2966 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7528.084 | 0.0144 | -0.9681 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7528.084 | 0.0114 | -0.9745 | 1.0247 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 9044.084 | 1.0237 | 1.1008 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 9044.084 | 1.2220 | 2.0449 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 9044.084 | 1.0543 | 1.2346 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 9044.084 | 1.0360 | 1.1541 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 9044.084 | 1.0049 | 1.0204 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 9044.084 | 0.9851 | 0.9379 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 9044.084 | 0.0521 | -0.9959 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 9044.084 | 0.0186 | -0.9995 | 0.4769 | |
| SUM1315MO2 | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 9044.084 | 0.0132 | -0.9998 | 0.4769 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7530.085 | 0.9930 | 0.9934 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7530.085 | 0.9376 | 0.9405 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7530.085 | 0.9395 | 0.9423 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7530.085 | 1.1388 | 1.1256 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7530.085 | 0.9992 | 0.9992 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7530.085 | 0.7634 | 0.7624 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7530.085 | 0.0606 | -0.4622 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7530.085 | 0.0091 | -0.7783 | 2.1343 | |
| SUM149PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7530.085 | 0.0073 | -0.8007 | 2.1343 |