Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7531.085 | 1.0624 | 1.0347 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7531.085 | 1.0592 | 1.0329 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7531.085 | 1.0946 | 1.0521 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7531.085 | 1.1015 | 1.0557 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7531.085 | 0.9669 | 0.9810 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7531.085 | 0.7136 | 0.8171 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7531.085 | 0.1099 | 0.0679 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7531.085 | 0.0005 | -0.7688 | 3.5188 | |
| SUM159PT | TNBC | Basal B | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7531.085 | 0.0005 | -0.7688 | 3.5188 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7532.084 | 1.0047 | 1.0121 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7532.084 | 0.9438 | 0.8566 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7532.084 | 0.9483 | 0.8680 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7532.084 | 0.9571 | 0.8903 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7532.084 | 0.7960 | 0.4911 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7532.084 | 0.3428 | -0.4957 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7532.084 | 0.0253 | -0.9824 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 6.67 | uM | 7532.084 | 0.0086 | -0.9956 | 0.7770 | |
| SUM185PE | TNBC | Luminal | Fascaplysin | CDK4 | CDK | 33.3 | uM | 7532.084 | 0.0040 | -0.9983 | 0.7770 | |
| SUM225CWN | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0000853 | uM | 7533.084 | 1.0008 | 1.0014 | 1.0396 | |
| SUM225CWN | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.000427 | uM | 7533.084 | 1.0592 | 1.1137 | 1.0396 | |
| SUM225CWN | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.00213 | uM | 7533.084 | 0.9447 | 0.8935 | 1.0396 | |
| SUM225CWN | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0107 | uM | 7533.084 | 1.0152 | 1.0293 | 1.0396 | |
| SUM225CWN | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.0533 | uM | 7533.084 | 0.9297 | 0.8646 | 1.0396 | |
| SUM225CWN | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 0.267 | uM | 7533.084 | 0.1486 | -0.6804 | 1.0396 | |
| SUM225CWN | HER2amp | Basal A | Fascaplysin | CDK4 | CDK | 1.33 | uM | 7533.084 | 0.0161 | -0.9624 | 1.0396 |