Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9648.132 | 0.9789 | 0.9411 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9648.132 | 0.9461 | 0.8507 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9648.132 | 0.9927 | 0.9795 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9648.132 | 0.7106 | 0.2401 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9648.132 | 0.9605 | 0.8904 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9648.132 | 0.9910 | 0.9747 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9648.132 | 0.8916 | 0.7033 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9648.132 | 0.7249 | 0.2751 | 0.7147 | |
| MDA-MB-361 | HER2amp | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9648.132 | 0.8384 | 0.5629 | 0.7147 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7897.016 | 1.0161 | 1.0443 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7897.016 | 0.8854 | 0.6929 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7897.016 | 1.0556 | 1.1538 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7897.016 | 1.0235 | 1.0646 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7897.016 | 1.0391 | 1.1079 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7897.016 | 0.9953 | 0.9871 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7897.016 | 1.0277 | 1.0763 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7897.016 | 0.8799 | 0.6784 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7897.016 | 0.5132 | -0.1981 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9664.049 | 1.0338 | 1.0946 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9664.049 | 1.0763 | 1.2154 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9664.049 | 1.0446 | 1.1250 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9664.049 | 1.0550 | 1.1546 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9664.049 | 1.0640 | 1.1803 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9664.049 | 1.1128 | 1.3203 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9664.049 | 1.1726 | 1.4955 | 0.7193 |