Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12070.16 | 0.7092 | 0.3319 | 0.8453 | ||
| CAMA-1 | HR+ | Luminal | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12070.16 | 0.6570 | 0.2168 | 0.8453 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000171 | uM | 12112.16 | 0.9666 | 0.9606 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000853 | uM | 12112.16 | 0.9526 | 0.9439 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00427 | uM | 12112.16 | 0.9831 | 0.9801 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0213 | uM | 12112.16 | 1.0025 | 1.0029 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.107 | uM | 12112.16 | 0.9774 | 0.9734 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.533 | uM | 12112.16 | 0.9605 | 0.9533 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 2.67 | uM | 12112.16 | 0.7398 | 0.6764 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 13.3 | uM | 12112.16 | 0.6385 | 0.5379 | 1.7073 | ||
| HCC1143 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 66.7 | uM | 12112.16 | 0.5076 | 0.3445 | 1.7073 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10518.138 | 1.0381 | 1.0565 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10518.138 | 0.9665 | 0.9498 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10518.138 | 0.9929 | 0.9895 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10518.138 | 0.9716 | 0.9575 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10518.138 | 0.9737 | 0.9606 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.267 | uM | 10518.138 | 0.7986 | 0.6912 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 1.33 | uM | 10518.138 | 0.4132 | 0.0348 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 6.67 | uM | 10518.138 | 0.3235 | -0.1379 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 33.3 | uM | 10518.138 | 0.2451 | -0.2990 | 1.3413 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0000853 | uM | 10753.15 | 1.0221 | 1.0311 | 1.4129 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.000427 | uM | 10753.15 | 0.8773 | 0.8230 | 1.4129 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.00213 | uM | 10753.15 | 0.9558 | 0.9371 | 1.4129 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0107 | uM | 10753.15 | 0.9374 | 0.9106 | 1.4129 | ||
| HCC1187 | TNBC | Basal A | Glycyl-H-1152 | ROCK2 | 0.0533 | uM | 10753.15 | 1.0024 | 1.0034 | 1.4129 |