Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 7453.091 | 0.8715 | 0.8344 | 1.5914 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 7453.091 | 0.7575 | 0.6797 | 1.5914 | |
| HCC1937 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 7453.091 | 0.6068 | 0.4611 | 1.5914 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7454.092 | 0.9469 | 0.9138 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7454.092 | 0.8216 | 0.7070 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7454.092 | 0.9493 | 0.9178 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7454.092 | 0.9922 | 0.9874 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7454.092 | 0.8957 | 0.8300 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.267 | uM | 7454.092 | 0.7155 | 0.5269 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 1.33 | uM | 7454.092 | 0.6961 | 0.4934 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 6.67 | uM | 7454.092 | 0.6179 | 0.3565 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 33.3 | uM | 7454.092 | 0.3904 | -0.0632 | 1.2402 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7455.092 | 1.2037 | 1.2363 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7455.092 | 1.0746 | 1.0886 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7455.092 | 1.0841 | 1.0997 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7455.092 | 1.1162 | 1.1369 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7455.092 | 1.1377 | 1.1616 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.267 | uM | 7455.092 | 0.9483 | 0.9370 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 1.33 | uM | 7455.092 | 0.8499 | 0.8134 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 6.67 | uM | 7455.092 | 0.7919 | 0.7378 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 33.3 | uM | 7455.092 | 0.4044 | 0.1595 | 1.6605 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7456.091 | 0.9857 | 0.9837 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7456.091 | 0.9605 | 0.9548 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7456.091 | 0.9589 | 0.9530 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7456.091 | 0.9474 | 0.9396 | 1.7629 |