Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12959.002 | 1.0929 | 1.5259 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12959.002 | 1.0342 | 1.1846 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12959.002 | 0.9931 | 0.9640 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 12959.002 | 0.8731 | 0.4002 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 12959.002 | 0.7220 | -0.1502 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 12959.002 | 0.6419 | -0.3761 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 12959.002 | 0.7055 | -0.2005 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 12959.002 | 0.7611 | -0.0240 | 0.3805 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7898.002 | 0.9712 | 0.9491 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7898.002 | 1.1346 | 1.2359 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7898.002 | 0.9939 | 0.9891 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7898.002 | 1.0365 | 1.0644 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 7898.002 | 0.7864 | 0.6177 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 7898.002 | 0.4218 | -0.0667 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 7898.002 | 0.4220 | -0.0662 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 7898.002 | 0.5274 | 0.1370 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 7898.002 | 0.5109 | 0.1055 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7900.002 | 1.0893 | 1.3950 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7900.002 | 1.1261 | 1.5683 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7900.002 | 1.2255 | 2.0693 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7900.002 | 1.2016 | 1.9447 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 7900.002 | 0.9685 | 0.8695 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 7900.002 | 0.6951 | -0.0704 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 7900.002 | 0.6906 | -0.0830 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 7900.002 | 0.5742 | -0.3784 | 0.4748 |