Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 7900.002 | 0.5910 | -0.3395 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10266.002 | 0.9770 | 0.9323 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10266.002 | 1.2177 | 1.6769 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10266.002 | 0.9404 | 0.8261 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10266.002 | 0.9619 | 0.8882 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 10266.002 | 0.6937 | 0.1641 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 10266.002 | 0.5613 | -0.1492 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 10266.002 | 0.5156 | -0.2496 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 10266.002 | 0.6261 | 0.0002 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 10266.002 | 0.5371 | -0.2028 | 0.6757 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7903.002 | 0.9850 | 0.9754 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7903.002 | 0.9688 | 0.9487 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7903.002 | 0.9980 | 0.9967 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7903.002 | 0.7571 | 0.5921 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7903.002 | 0.2534 | -0.3508 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7903.002 | 0.1994 | -0.4666 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7903.002 | 0.1904 | -0.4863 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7903.002 | 0.2175 | -0.4272 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7903.002 | 0.2597 | -0.3375 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9708.002 | 0.9991 | 0.9983 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9708.002 | 1.1009 | 1.1921 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9708.002 | 0.9265 | 0.8596 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9708.002 | 0.8103 | 0.6364 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9708.002 | 0.4565 | -0.0536 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9708.002 | 0.3913 | -0.1828 | 1.0482 |