Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	12989.002	0.9535	0.8480	0.6028
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	12989.002	0.6610	0.0063	0.6028
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	12989.002	0.5639	-0.2270	0.6028
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	12989.002	0.5705	-0.2119	0.6028
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	2	uM	12989.002	0.5442	-0.2712	0.6028
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	10	uM	12989.002	0.5593	-0.2373	0.6028
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	7897.002	0.9918	0.9805	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	7897.002	0.9690	0.9262	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	7897.002	0.9820	0.9571	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	7897.002	0.7396	0.3954	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	7897.002	0.6508	0.1980	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	7897.002	0.5406	-0.0400	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	7897.002	0.5787	0.0413	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	2	uM	7897.002	0.5986	0.0843	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	10	uM	7897.002	0.5840	0.0526	0.8381
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	9664.002	1.0170	1.0573	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	9664.002	1.0364	1.1239	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	9664.002	1.0002	1.0008	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	9664.002	0.7486	0.2289	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	9664.002	0.5992	-0.1548	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	9664.002	0.4859	-0.4059	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	9664.002	0.4882	-0.4010	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	2	uM	9664.002	0.5638	-0.2371	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	10	uM	9664.002	0.5729	-0.2163	0.5947
MDA-MB-415	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	12959.002	1.0411	1.2231	0.3805

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)