Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.08 | uM | 10124.002 | 0.3069 | 0.1333 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.4 | uM | 10124.002 | 0.3394 | 0.1895 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 2 | uM | 10124.002 | 0.2892 | 0.1013 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 10 | uM | 10124.002 | 0.3069 | 0.1333 | 2.0795 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10147.002 | 1.1215 | 1.1202 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10147.002 | 1.1363 | 1.1345 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10147.002 | 0.8413 | 0.8315 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10147.002 | 0.4157 | 0.2791 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.016 | uM | 10147.002 | 0.1173 | -0.3284 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.08 | uM | 10147.002 | 0.1278 | -0.2984 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.4 | uM | 10147.002 | 0.1080 | -0.3559 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 2 | uM | 10147.002 | 0.1593 | -0.2150 | 1.9641 | |
| HMT-3522 T4-2 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 10 | uM | 10147.002 | 0.2115 | -0.0931 | 1.9641 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7864.002 | 0.9398 | 0.9234 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7864.002 | 0.8505 | 0.8065 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7864.002 | 0.8483 | 0.8035 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7864.002 | 0.5579 | 0.3859 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 7864.002 | 0.2441 | -0.1758 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 7864.002 | 0.1524 | -0.3869 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 7864.002 | 0.1260 | -0.4559 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 7864.002 | 0.1402 | -0.4182 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 7864.002 | 0.1921 | -0.2910 | 1.5910 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9511.002 | 1.0093 | 1.0156 | 1.1960 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9511.002 | 1.0100 | 1.0167 | 1.1960 | |
| Hs 578T | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9511.002 | 0.9272 | 0.8775 | 1.1960 |