Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7857.002 | 0.3041 | -0.2632 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7857.002 | 0.3451 | -0.1807 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9501.002 | 0.9869 | 0.9741 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9501.002 | 1.0430 | 1.0854 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9501.002 | 0.9696 | 0.9397 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9501.002 | 0.6973 | 0.3987 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 9501.002 | 0.4556 | -0.0829 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 9501.002 | 0.1686 | -0.6579 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 9501.002 | 0.1875 | -0.6199 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 9501.002 | 0.2345 | -0.5255 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 9501.002 | 0.2692 | -0.4558 | 1.0082 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12714.002 | 1.0116 | 1.0538 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12714.002 | 1.0444 | 1.2112 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12714.002 | 1.0110 | 1.0512 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12714.002 | 0.8236 | 0.2771 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 12714.002 | 0.5471 | -0.5036 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 12714.002 | 0.2580 | -0.9126 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 12714.002 | 0.2906 | -0.8849 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 12714.002 | 0.4315 | -0.7131 | 0.4328 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 12714.002 | 0.4951 | -0.6059 | 0.4328 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10124.002 | 1.1774 | 1.1634 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10124.002 | 1.0083 | 1.0079 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10124.002 | 0.8861 | 0.8871 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10124.002 | 0.7435 | 0.7343 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Docetaxel | TUBB | TUBB | 0.016 | uM | 10124.002 | 0.3548 | 0.2150 | 2.0795 |