Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12696.002 | 0.9993 | 0.9980 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12696.002 | 1.0231 | 1.0647 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12696.002 | 0.9406 | 0.8365 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12696.002 | 0.6691 | 0.1432 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 12696.002 | 0.4007 | -0.4401 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 12696.002 | 0.0423 | -0.9755 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 12696.002 | 0.0429 | -0.9750 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 12696.002 | 0.0463 | -0.9723 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 12696.002 | 0.0538 | -0.9658 | 0.7184 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7813.002 | 0.8297 | 0.6042 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7813.002 | 1.0693 | 1.1648 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7813.002 | 1.1561 | 1.3740 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7813.002 | 0.8533 | 0.6581 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 7813.002 | 0.4502 | -0.2210 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 7813.002 | 0.3425 | -0.4360 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 7813.002 | 0.4058 | -0.3110 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 7813.002 | 0.3614 | -0.3992 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 7813.002 | 0.3647 | -0.3926 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9254.002 | 1.3450 | 3.2091 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9254.002 | 1.3333 | 3.1181 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9254.002 | 1.3707 | 3.4141 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9254.002 | 1.1643 | 1.9299 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 9254.002 | 0.5744 | -0.5028 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 9254.002 | 0.5017 | -0.6460 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 9254.002 | 0.4537 | -0.7250 | 0.3983 |