Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7811.002 | 0.9822 | 0.9285 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7811.002 | 0.8469 | 0.4275 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7811.002 | 0.4020 | -0.6851 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7811.002 | 0.0802 | -0.9880 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7811.002 | 0.0852 | -0.9865 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7811.002 | 0.0792 | -0.9883 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7811.002 | 0.0802 | -0.9881 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7812.002 | 1.0257 | 1.0478 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7812.002 | 1.1411 | 1.2618 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7812.002 | 1.0805 | 1.1497 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7812.002 | 0.5636 | 0.1720 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7812.002 | 0.2922 | -0.3645 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7812.002 | 0.0775 | -0.8155 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7812.002 | 0.0773 | -0.8159 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7812.002 | 0.0853 | -0.7983 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7812.002 | 0.0971 | -0.7724 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9244.002 | 1.0998 | 1.4008 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9244.002 | 1.1777 | 1.7382 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9244.002 | 1.0606 | 1.2392 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9244.002 | 0.6996 | 0.0071 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 9244.002 | 0.4775 | -0.5165 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 9244.002 | 0.0739 | -0.9866 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 9244.002 | 0.0449 | -0.9948 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 9244.002 | 0.0475 | -0.9943 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 9244.002 | 0.0412 | -0.9956 | 0.5206 |