Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13078.174 | 0.9747 | 0.9195 | 0.6238 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13078.174 | 0.9882 | 0.9624 | 0.6238 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13078.174 | 0.6725 | 0.0589 | 0.6238 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13078.174 | 0.3284 | -0.6644 | 0.6238 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13078.174 | 0.3102 | -0.6937 | 0.6238 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13078.174 | 0.5448 | -0.2445 | 0.6238 | |
| UACC-812 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13078.174 | 0.5127 | -0.3146 | 0.6238 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12677.174 | 0.9283 | 0.8564 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12677.174 | 1.0000 | 1.0000 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12677.174 | 0.9694 | 0.9388 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12677.174 | 0.9683 | 0.9365 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12677.174 | 0.6844 | 0.3683 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12677.174 | 0.5178 | 0.0350 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12677.174 | 0.9000 | 0.7998 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12677.174 | 0.7846 | 0.5690 | 0.9992 | |
| ZR-75-1 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12677.174 | 0.7122 | 0.4240 | 0.9992 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13595.174 | 0.9720 | 0.9697 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13595.174 | 0.9678 | 0.9652 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13595.174 | 1.0300 | 1.0321 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13595.174 | 1.0089 | 1.0095 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13595.174 | 0.7922 | 0.7645 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13595.174 | 0.5556 | 0.4581 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13595.174 | 0.7591 | 0.7245 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13595.174 | 0.7796 | 0.7493 | 1.8596 | |
| ZR75B | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13595.174 | 0.2783 | 0.0054 | 1.8596 |